KUSI Newsroom, KUSI Newsroom January 4, 2018 Posted: January 4, 2018 SAN DIEGO (KUSI) — In a ”mad dash” to take advantage of uncapped property tax deductions before the new tax law went into effect this year, 25 percent of San Diego County property owners paid their bills early, the county treasurer’s office said Thursday.The office of Treasurer-Tax Collector Dan McAllister received almost 72,000 more second installment property tax payments than this time last year. Some 41,000 of those payments were made in the last three days of 2018, McAllister said.The office received 255,407 second installment payments before Jan. 1, compared to 183,808 by the same time last year, according to the treasurer’s office.Property tax payments are due in two installments, on Nov. 1 and April 10.Many people who paid their second installment before the beginning of this year were looking to take advantage of the unlimited property tax dedications for federal income tax under the old set of rules, McAllister said.Under the new system signed into law by President Trump in December, people can only deduct up to $10,000 in property, state and local tax payments from their federal tax burden.Prepaying property taxes could be advantageous for those who itemize their taxes, usually pay more than $10,000 in state and local taxes and are not subject to the Alternative Minimum Tax, tax experts told various media outlets. 25% of San Diego property owners paid bills early to avoid new tax laws Categories: Local San Diego News FacebookTwitter
April 26, 2018 KUSI Newsroom SAN DIEGO (KUSI) — San Diego State University Athletic Director John David Wicker said Thursday the university’s proposed 35,000-seat Mission Valley stadium could expand to 55,000 seats to accommodate a future NFL franchise.The stadium would include 82 suites located among the field level, lower bowl sideline, upper sideline and five club sections. It would also feature 50 loge boxes with lounges.A perforated aluminum panel exterior “influenced by the sailboats found in San Diego Harbor” would change colors throughout the day, Wicker said.The site would also feature about 90,000 square feet of retail space, located near the stadium, which would serve residents, employees, students and visitors during non-game days.The proposed stadium is being designed by Populous, a global architecture and design firm that has designed more than 2,000 projects over the last 30 years, including Yankee Stadium. KUSI Newsroom, Posted: April 26, 2018 SDSU Athletic Director says proposed Mission Valley stadium could accommodate a future NFL franchise Categories: Local San Diego News FacebookTwitter
Google headquarters in Mountain View, California. Stephen Shankland/CNET Google used shell companies and subsidiaries to hide its involvement in expansion plans that yielded millions of dollars in tax breaks, according to a report by The Washington Post on Friday, casting light on how tech companies cut deals with local governments. When the search giant planned to build a data center in Midlothian, Texas, Google used a subsidiary called Sharka LLC, The Post reported. Other subsidiaries Google set up for development projects include Jet Stream LLC and Questa LLC. Google also extensively uses non-disclosure agreements with officials, The Post said. In the case of the Texas data center, Google was seeking a decade of tax breaks, but Midlothian’s head of economic development was barred from disclosing Google’s involvement in the project, the report said. The size of deals between local governments and tech companies was thrust into the spotlight Thursday after Amazon dropped a bombshell announcement: It was no longer going forward with plans to build a massive second headquarters in New York City. The withdrawal followed intense opposition from local politicians and union groups, fueled in part by the tax breaks the city gave the e-commerce giant.Deal-making is crucial for Google as it revs up expansion. Earlier this week, CEO Sundar Pichai said the search giant is investing $13 billion in data centers and offices around the country, mostly in the Midwest, East Coast and South. That includes new and expanded data centers in Ohio, Nebraska, Oklahoma, South Carolina and Texas. New and expanded office locations include sites in Virginia, Georgia and Chicago.In California, Google is building a giant campus in San Jose, about 15 miles from the company’s headquarters in Mountain View. The new San Jose outpost will be Google’s second-largest campus. Partnership for Working Families, which obtained the Google records and shared them with The Post, has sued the city of San Jose over its negotiations with Google. The advocacy group didn’t respond to a request for comment. A Google spokeswoman called its tactics “standard industry practices.” At the early stages of deals, companies often strive to keep negotiations quiet because they don’t want to tip off competitors or announce their plans prematurely. But some critics have pointed to the secrecy as detrimental to local communities, which sometimes can’t protest until it’s too late.”We believe public dialogue is vital to the process of building new sites and offices, so we actively engage with community members and elected officials in the places we call home,” the Google spokeswoman said in a statement. “Of course, when we enter new communities we use common industry practices and work with municipalities to follow their required procedures.”Still, tamping down concerns from local communities will be an ongoing battle for tech giants, as Silicon Valley faces more scrutiny than ever over its scale and influence. On Friday, Google tried to highlight some of the benefits of its expansion. The company said Google’s data centers create $1.3 billion in economic activity, $750 million in labor income, and 11,000 jobs throughout the US in a single year. Google Alphabet Inc. 4 Comments Tags Tech Industry Share your voice
PixabayA recent video uploaded to YouTube by popular conspiracy theory channel ‘Third Phase of Moon’ is now the hottest debating point among conspiracy theorists and alien enthusiasts. In the video, three Los Angeles Police Department (LAPD) helicopters can be seen encountering a black UFO that seems to be staying intact in the sky.Interestingly, the incident happened in broad daylight, and we can clearly see the black UFO staying stationary in the skies just in front of the police helicopters. “Three helicopters and a dot. That’s a UFO right there. The helicopters are facing that dot,” said the unnamed eyewitness who shot the event on the camera.The video uploaded by the Third Phase of Moon soon went viral on YouTube, and it has already racked up more than 40,000 views.”We are wondering if this is a standoff between extraterrestrial existence, a craft from another world and LAPD helicopters. Basically, this might be some kind of Mexican standoff. What the heck is going on in the skies over LA? This video does not look like an edited video, and there are no traces of tampering,” said conspiracy theorists Blake Cousins in the YouTube video.After watching the video, most of the viewers of this conspiracy theory channel admitted that alien life is a reality, and some people even went a step ahead and argued that extraterrestrials are now gearing up for disclosure.”With these helicopters viewing these craft, it makes me wonder what they are and if possible what they are recording from the choppers. We are living in strange times where we are now seeing things in plain daylight, it can’t be ignored or covered up anymore,” commented Damen Rebel, a YouTube user.”They know extraterrestrials exist, it’s obvious. They also do appear to be very hesitant about them. With the immense technology, some aliens have ( in our solar system), then no wonder,” commented Frank Hall, another YouTuber.However, some sceptics suggested that the weird UFO in the skies and helicopters encountering it could be actually a progressing film shooting. Some others claimed that the UFO might be a balloon.
China National Chemical Corp is in talks to buy Switzerland’s Syngenta AG but its initial offer of nearly $42 billion for the world’s largest agrichemical company was rejected, Bloomberg said on Thursday.State-owned ChemChina’s first offer valued the agricultural chemicals group at 449 Swiss francs per share, or 41.7 billion Swiss francs ($41.72 billion), according to Bloomberg.Citing unidentified sources, it said the rejection stemmed from regulatory concerns. The two companies have not broken off talks and an agreement could still be reached in the next few weeks, Bloomberg said.Syngenta, under pressure to offer value to shareholders after turning down a big offer from Monsanto Co earlier this year, is also talking to other potential suitors, according to Bloomberg.U.S.-listed shares of Syngenta were up 14% at $79.22 in extended trading on Thursday.Syngenta and ChemChina could not immediately be reached for comment.Syngenta rejected Monsanto’s cash plus stock offer in August. The offer was worth about $47 billion and Syngenta said it “significantly undervalued the company.”At the time, some shareholders expressed disappointment over the spurned deal and questioned the company’s ability to improve its financial fortunes in a slumping commodity market.To appease shareholders, Syngenta announced plans in September to buy back more than $2 billion of stock, funding the measure by selling its vegetable seeds business.
Indian school children prepare for their Central Board of Secondary Education (CBSE)Raveendran/AFP/Getty ImagesThe much-awaited results of CBSE class 10 exams were announced on Tuesday. Over 91 per cent students passed this year’s examination and 13 students scored 499 out of 500 marks. One among them is Bhavana, who hails from Kerala’s Palakkad district and is a student of Lions School in Koppam.Interestingly, two other students from Kerala – Atheena Elsa Roy from Silver Hills Public School in Kozhikode and Sirinsa Xavier from Vimal Jyothi Central School in Thrissur – scored 498 marks each.The regions in India with the highest winning percentage are Thiruvananthapuram (99.85), Chennai (99) and Ajmer (95.89).Union HRD Minister Prakash Javedekar congratulated all the students who passed the examination and revealed that government schools have also fared well this time.The CBSE class 10 examinations were conducted from February 21 to March 29. As per reports, more than 18 lakh students appeared for this year’s examination. The valuation process was conducted in a very meticulous manner, and CBSE successfully revealed the results within 38 days after the completion of the examination.In the meantime, the Kerala Board of Secondary Education also released the SSLC results on Tuesday. Over 98 per cent students passed this year’s examination and 37,334 scored full A+ grades in all subjects.Pathanamthitta district in Kerala recorded the best performance with 99.3 per cent students passing the exam.
Kolkata: The state Fire and Emergency Services department is planning to include fire safety and security measures in the school curriculum. “It is important for everyone to have knowledge about safety and security from the fire. So we are working on introducing it in the school syllabus,” state Fire and Emergency Services minister Sovan Chatterjee said at a programme on Fire Services Week at Academy of Fine Arts on Saturday. According to Chatterjee, the state government has given a major boost in developing the infrastructure of the Fire department and has set up as many as 70 fire stations across the state since 2011 after the Trinamool Congress came to power. Also Read – Heavy rain hits traffic, flights”We have identified some fire-prone areas and some regions where the fire tenders face difficulty to enter because of narrow lanes and bylanes. We have procured modern equipment and are still continuing to do so to fight the fire at places where it is difficult to reach,” Chatterjee said.He added that under the instructions of Chief Minister Mamata Banerjee, the department is procuring ladders for better fire-fighting in the high-rises. “We have already floated the tender for procuring ladders,” he said.Officials from the fire department demonstrated how preliminary fire-fighting measures may be implemented to prevent it from spreading. A number of school students and commoners were present during the demonstration. Director General of Fire Services department Jagmohan also attend the event along with other senior officials of the department.
Kolkata: The Special Task Force (STF) of Kolkata Police nabbed a Fake Indian Currency Note (FICN) racketeer identified as Majibur Shaikh, a resident of Baishnabnagar, from Malda on Monday evening. Investigators have recovered FICN worth Rs 5 lakh from him.Sources informed that Shaikh’s name came up to the STF investigators, following the arrest of three FICN racketeers in the month of July. Following the arrest of the trio, investigators had recovered FICN of Rs 500 denomination worth Rs 1 lakh, along with forty semi-finished improvised firearms. Also Read – Rain batters Kolkata, cripples normal lifeFollowing the interrogation process, STF raided an illegal arms factory at Kankinara in Jagaddal. Twenty pieces of semi-finished firearms, one lathe machine, two drilling machines and several parts of improvised firearms were seized from the factory. Six persons working in the illegal workshop were arrested.During the follow up investigation, investigators came up with Shaikh’s name. On Monday, acting on a tip-off, an STF team was waiting for Shaikh at the Esplanade bus terminus. When he got down from a bus, STF personnel surrounded him.After checking his bag, 250 fake notes of Rs 2,000 denomination were found. The investigators are suspecting that Majibur might have connection with international FICN rackets.
Posted by TORONTO — Air Italy says all of the routes in its current summer season will be back for next year’s summer season, starting March 29 and running through Oct. 24, 2020.The carrier’s Toronto-Milan flights are coming back next year, along with flights out of L.A. and San Francisco. Air Italy also offers year-round services out of New York and Miami.In addition to the above routes, all of the current 2019 summer schedule to Africa – Cairo, Dakar, Accra, Lagos and Sharm el Sheikh – are also on sale for 2020.Air Italy will also be continuing to serve daily multi-frequencies and connections with international flights from Rome, Naples, Palermo, Catania, Lamezia Terme, Cagliari and Olbia.“Due to the excellent performance of our network during 2019, we are very pleased to be able to announce the commencement of sales for 2020 with the entire network remaining for next summer,” said Rossen Dimitrov, Chief Operating Officer. “This demonstrates our commitment to both the domestic and international market, our network strategy, and our desire to enhance the travel experience for our passengers once more, through early planning opportunities and continued service to our popular destinations.”More news: Le Boat has EBBs along with its new 2020 brochureMilan Malpensa (MPX) remains at the core of Air Italy’s 2020 network, says Dimitrov, with more than 170 weekly frequencies operating from the carrier’s main hub in the peak season. Some 26 of those are North Atlantic routes, including the six times weekly summer seasonal service from Toronto. The service launched in May 2019.During the winter season 2019/2020, adds Rossen, Air Italy will operate new long-haul seasonal destinations such as Maldives – which will be offered until the end of 2020 Easter holidays – alongside Mombasa and Zanzibar. These new routes will be launched in October 2019 and will be operated by the airline’s A330-200 aircraft during the winter. Share Air Italy opens Toronto-Milan sales for summer 2020 Tags: Air Italy, Milan, Sales Monday, July 15, 2019 Travelweek Group << Previous PostNext Post >>
Known locally as ‘Team Kerr’, parents David and Sandra are regularly spotted attending races across Northern Ireland whilst pushing their son Aaron, who has complex needs, in a custom-built wheelchair. For the family, running together has become a way of life. Dad David Kerr said: “We’re really looking forward to taking part in this year’s Run Together series. “Running has opened a whole new avenue for us. We are full-time carers and look after Aaron 24/7. “To have running as a release is fantastic for all of us and it has become our social life. “Aaron is a different boy than he used to be. He is at his happiest with the wind in his hair and the sun on his face. “He has friends that he sees at every event, his confidence has grown, his health has improved, and we are visiting places as a family that we would never get the chance to visit in the day chair.” Building on the success of the initiative over the last three years, this year’s Run Together series hopes to make an even bigger impact with the addition of a more challenging 10K race at Ormeau Park, Belfast. This new and exciting 10K event will act as a big finale, ending the series on a high during Centra’s annual fundraising week in October.For this final event, a small entry fee will apply to both the 5K and 10K races, with 100% of the fee donated to Action Cancer. It is hoped that this event will raise over £20,000 for the charity, as Centra edges closer to its major £3million fundraising target.This year alone, Centra’s fundraising has contributed to 4,339 breast screenings, with 222 of these being referred for further tests. The funds have also allowed the Health Action Programme to visit 163 schools across the North of Ireland, reaching 9387 pupils. The programme is designed to improve knowledge of health and encourage pupils at nursery, primary and secondary school levels to take ownership of their lifestyle choices. Commenting on the series, Jennifer Morton, Centra brand manager, said: “The Centra Run Together series has established itself as a popular part of our Live Well initiative. “Our evening race in Derry has always been a popular event, and we are looking forward to returning for a fourth year. “As always, our aim is to encourage as many people to get up, get active and embrace the community spirit of the series, whether they are a frequent runner or a first-timer. “Once again, we are delighted to have Deep RiverRock back on board as our title sponsor. With their help, we look forward to building on the success of previous years and raising even more money for Action Cancer in 2019.” Orla McKenna from Deep RiverRock said: “On behalf of Deep RiverRock, a much loved locally sourced water from the North of Ireland, we’re are delighted to be involved in the Run Together series once again this year. “Deep RiverRock’s ‘Thirst For Better’ platform is about connecting people in their collective pursuits, and fostering great community spirit; a message that resonates perfectly with Centra’s Live Well campaign. “We look forward to supporting those new and seasoned runners to come together and have some fun, while getting active.” For further information and details of how to register visit www.centra.co.uk/runtogether or the Centra Facebook page, www.facebook.com/CentraNI Final call: Centra run together encourages Derry to get up and running in 2019 was last modified: June 4th, 2019 by John2John2 Tags: Action CancerBUNCRANA ROADcentraDeep River RockFinal call: Centra run together encourages Derry to get up and running in 2019QUEEN’S QUAY The event is an integral part of Centra’s Live Well platform, which helps people to make healthier food and lifestyle choices. Runners are encouraged to enter the race in pairs, motivating families to participate together, whilst raising vital funds for Action Cancer – you can run, jog or walk with a friend, kids or even the dog. Everyone that takes part will receive a free T-shirt, bespoke Centra Run Together medal, a free lunch and tasty samples courtesy of Deep RiverRock, Müller, Alpro, Fridge Raiders and Fulfil, with race packs being made available at Centra Buncrana Road. Participating in this year’s series are family David, Sandra and Aaron Kerr, previous participants in the Walled City Marathon. Local convenience retailer Centra is calling upon people from County Derry to get up and running for the second event in its annual Run Together series, which has returned bigger and better than ever for 2019.WITH marathon fever alive in the city, local convenience retailer Centra has issued a final call to the people Derry and beyond, encouraging everyone to put their best foot forward and sign up for the third regional 5K race of the series at Queen’s Quay in the city next Wednesday, June 12.The Centra Run Together series is designed to encourage people of all ages and abilities to adopt an active lifestyle and get up and run together in a series of free 5K runs across the North of Ireland. ShareTweet
The same pattern has played out again and again around the world and throughout history. The worse a government’s fiscal health gets, the more destructive its policies become.This is the root of political risk.It’s no secret that political risk is snowballing in many parts of the world. This is especially true in the US and Europe, where welfare and warfare spending continues unabated. It doesn’t matter which party is in power.But no matter where you live, international diversification can greatly reduce the threat your home government poses to your personal and financial well-being.You know the benefits of diversifying your investment portfolio. If you put all of your asset eggs in one basket, you could lose your entire portfolio if that basket breaks.The same idea applies to political risk. If your home country “breaks”—and turns to the destructive policies I just mentioned—you could lose everything.Most people have medical, life, fire, and car insurance. You hope you never have to use these policies, but you have them anyway. They give you peace of mind and protect you if and when the worst does happen.International diversification is the ultimate insurance policy against an out-of-control government. Think of it as “freedom insurance.”It frees you from absolute dependence on any one country. Achieve that freedom, and it becomes very difficult for any group of bureaucrats to control you.The results can be life-changing. Recommended Link [EXPIRES MIDNIGHT] Today is your last chance to get the top pick of one of the most successful analysts in Bill Bonner’s network… and lock in a free year of one of his most popular research services. Click here for all the details. — Justin’s note: As longtime readers know, owning gold for the long term is one of our core recommendations here at Casey Research. And it’s now more important than ever. That’s because every day, the window to protect your personal and financial freedom closes a bit more.Today, we’re handing the reins to Crisis Investing editor Nick Giambruno to explain why… By Nick Giambruno, editor, Crisis InvestingIt’s predictable…A government in need of cash will turn to destructive “solutions.”Money printing, higher taxes, and more regulations often come first. Unfortunately, these are just the hors d’oeuvres before a 10-course meal.As they become increasingly desperate, governments implement increasingly destructive policies. This might include capital controls, price controls, people controls, official currency devaluations, wealth confiscations, retirement account nationalizations, and more. Less than 10 people in the world know about thisTrue breakthroughs rarely happen in the world of market trading… But this is one of them. Developed in secrecy over five years, it’s a never-before-seen indicator of short-term stock profit opportunities. Only a handful of people know about this data-proven 93.5%-accurate way of picking future market wins… But now we’re throwing back the veil on it — so that YOU can get rich. Discover it now by clicking here. The Easiest First StepIt’s crucial to place some of your savings beyond the easy reach of your home government. It keeps that government from trapping your money if and when it implements capital controls or outright asset seizures. Any government can do either without warning.The ultimate way to diversify your savings is to transfer it out of the immediate reach of your home government and into something tangible.Something that cannot be easily confiscated, nationalized, frozen, or devalued at the drop of a hat or with a couple of taps on the keyboard—while retaining as much privacy as legally possible.Something whose value is recognized around the world and is not controlled by any government.Gold (and silver) fit the bill perfectly.There is nothing particularly American, Chinese, Russian, or European about gold. Different civilizations have used it as money for millennia. It’s always been an inherently international asset.Buying gold is perhaps the easiest step you can take towards diversifying your savings.When you buy gold, you trade in paper money—which the government can devalue and confiscate at will—for a hard asset that’s been a stable store of value for thousands of years.Gold is universally valued. Its worth doesn’t depend on any government.In other words, simply buying gold is the easiest way to lessen the political risk to your savings.Freedom InsuranceSomehow, someway, your home government will keep squeezing your pocketbook harder. It will keep subjecting you to escalating, arbitrary, and burdensome regulations and restrictions.Expect more government and less freedom all around.With each passing week, the window to protect your personal and financial freedom closes a bit more.Fortunately, you don’t need to be hostage to a desperate and out-of-control government.International diversification is a time-tested route to freedom. Wealthy people around the world have used it for centuries to effectively protect their money and their families.Buying gold is an important first step.Regards,Nick GiambrunoEditor, Crisis InvestingP.S. Buying gold is where to start. But there’s much more to do…The US government gets bigger, more invasive, and more aggressive by the day. But you can take concrete steps to protect yourself from this hostile giant.That’s why New York Times best-selling author Doug Casey and I just released an urgent video that explains more about the crisis that’s about to hit America…and why it’s so important that you take action today.You can learn more right here. Recommended Link —
The attorney general of Oklahoma goes to court in an unprecedented case this week.The state is charging drugmaker Johnson & Johnson with “a cynical, deceitful multimillion dollar brainwashing campaign” in order to sell opioids, according to The Guardian..The civil case is the first time a pharmaceutical company has gone to court over responsibility for the opioid epidemic. The Department of Health and Human Services estimates that more than 130 people died every day in 2017 due to opioid-related causes.The case comes amid another landmark lawsuit filed in March against Purdue Pharma LP, the company behind the narcotic OxyContin. “More than 600 cities, counties and Native American tribes from 28 states have filed a federal lawsuit against eight members of the Sackler family,” CNN reported. The Sackler family owns Purdue Pharma.More from CNN:Like other suits that have been filed, this one alleges the Sackler family made a fortune by using deceptive marketing to sell addictive and potentially deadly painkillers.“Eight people in a single family made the choices that caused much of the opioid epidemic,” the suit says, then naming the eight defendants.“Because they controlled their own privately held drug company, the Sackler Defendants had the power to decide how addictive narcotics were sold. They got more patients on opioids, at higher doses, for longer, than ever before. They paid themselves billions of dollars. They are responsible for addiction, overdose, and death that damaged millions of lives. They should be held accountable now.”What would justice look like for those who have been affected by the opioid epidemic? Who is to blame for the crisis?Produced by Jonquilyn Hill.GUESTSJackie Fortier, Senior health care reporter, StateImpact Oklahoma; @JackieFortierKatie Zezima, National reporter, The Washington Post; @katiezezBrian Frosh, Attorney General, MarylandTom Miller, Attorney General, IowaFor more, visit https://the1a.org.© 2019 WAMU 88.5 – American University Radio. Copyright 2019 WAMU 88.5. To see more, visit WAMU 88.5.
Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. Add to Queue This story originally appeared on Business Insider –shares The New York-based company’s main business is now licensing its location data to other companies like American Express and Land Rover. Next Article After Inventing the Check-in, Foursquare Pivots With Efforts to Sell its Location Superpowers to Everyone Foursquare has gone through a profound transformation since it popularized the concept of the “check-in” back in 2009.The New York-based company’s main business is now licensing its location data to other companies like American Express, Pinterest and Land Rover. When you use a geofilter in Snapchat or type a venue name into Uber, you’re using Foursquare data.What’s led so many companies to rely on Foursquare’s location technology?For starters, there are the more than 10 billion check-ins that Foursquare’s 50 million monthly users have registered to date. But the company’s real “superpower,” according to founder and chairman Dennis Crowley, is something called Pilgrim. And starting Wednesday, Foursquare is making Pilgrim available to all apps for the first time.“We live in a world today where people are building things based off of basic GPS coordinates,” Crowley told Business Insider during a recent interview. With Pilgrim, Foursquare can give other apps and marketers “specific awareness of context in space” — a “big idea” Crowley said will “take time for people to wrap their heads around.”While traditional GPS can see when a phone enters a mall, Foursquare’s Pilgrim technology is able to understand that the phone is on the second floor of said mall and inside a J Crew store for the second time. It’s by analyzing this data that Foursquare has been able to accurately predict everything from iPhone to Chipotle sales.Crowley envisions other companies using Pilgrim to send notifications like hyper-specific coupons and even create Pokémon Go-like games that “change based upon where you bring your phone.” Foursquare’s main app has been using Pilgrim for years to send custom-tailored recommendations based on where its users go in the real world.For Crowley, who first made his name by selling his location-based social network Dodgeball to Google in 2005, opening up Pilgrim is the culmination of Foursquare’s seven-year history. While the company won’t disclose actual numbers, Crowley said that “revenue is growing nicely” and that the business is in “a really healthy spot right now.”“We always thought that someone would come along and make something like the Pilgrim SDK and we would just use it,” he said. “I don’t think we imagined way back in the day that we would be the company to actually bring this to market.” Tech Reporter for Business Insider Image credit: Foursquare 3 min read Foursquare March 2, 2017 Alex Heath Foursquare’s Steven Rosenblatt (president), Dennis Crowley (founder and executive chairman), Jeff Glueck (CEO). Enroll Now for $5
Mt. Gox’s website is mysteriously back up and Blockchain.info is frustratingly down. Ah, the roller coaster drama Bitcoin users endure.Blockchain.info crashes, but funds remain unscathed Blockchain.info, Bitcoin’s most popular Bitcoin wallet and block explorer service, blames a “bug in some database handling code” for causing an ongoing outage. Its site now reads “We Will Be Back Shortly,” and directs visitors to the company’s Twitter feed for updates. We’re still working on the server issue, & are looking at a phased approach to bring the services online one at time. More updates to come.— Blockchain.info (@blockchain) March 18, 2014 Add to Queue Blockchain Limited Chief Security Officer Andreas M. Antonopoulos said on the company’s blog yesterday that the outage “may last more than an hour.” That was nearly 20 hours ago. A more recent blog post reports that the company is “working around the clock” to fix the problem.Related: ‘I Did Not Create Bitcoin’: 4 Major Takeaways From Dorian Satoshi Nakamoto’s Letter of DenialBlockchain.info houses some 1.4 million Bitcoin wallets, all of which Antonopoulos said are “safe” while the site is offline. He also noted that the “security of funds and the completion of executed transactions” also remain unaffected by the outage.“Unlike other services that have ownership over private keys, Blockchain is superior because it allows users to access their private keys, thus enabling them to have access to their funds under circumstances such as this,” a blog post by the “Blockchain Team” reads.Related: One-Time Bitcoin Exchange Giant Mt. Gox Collapses Amid Insolvency, Trading Allegedly Suspended Addressing mounting customer concerns, the company also posted instructions on how to import Blockchain.info funds into a Bitcoin wallet client called MultiBit. Blockchain.info customers who don’t have a wallet backup are being asked to fill out a helpdesk request. Mt. Gox resurrects its website…Kind ofMeanwhile, signs of life are showing over at troubled Bitcoin exchange Mt. Gox. Its website, which went blank last month, is now mysteriously back up and letting users log in and check their wallet balances.But not without a hefty legal disclaimer:This balance confirmation service is provided on this site only for the convenience of all users.Please be aware that confirming the balance on this site does not constitute a filing of rehabilitation claims under the civil rehabilitation procedure and note that the balance amounts shown on this site should also not be considered an acknowledgment by MtGox Co., Ltd. of the amount of any rehabilitation claims of users.Rehabilitation claims under a civil rehabilitation procedure become confirmed from a filing which is followed by an investigation procedure. The method for filing claims will be published on this site as soon as we will be in situation to announce it.So Mt. Gox customers can at last check their balances, but they still don’t know if they’ll ever be able to retrieve their money, even partially. March 18, 2014 2019 Entrepreneur 360 List Image credit: 360b / Shutterstock.com Bitcoin Former West Coast Editor Next Article 3 min read –shares Glitch Sparks Ongoing Blockchain Outage; Mt. Gox Resurrects Site to Let Users Check Balances Kim Lachance Shandrow The only list that measures privately-held company performance across multiple dimensions—not just revenue. Apply Now »
Source:http://news.vumc.org/2019/04/24/big-data-zebrafish-biology-disease/ Reviewed by James Ives, M.Psych. (Editor)Apr 25 2019In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.The research uncovered an unexpected role for the gene GRIK5, and it showcases a new paradigm for using biobanks, electronic health records and zebrafish to discover the genetic mechanisms that contribute to human disease. The findings were reported in the American Journal of Human Genetics.The back-and-forth approach primarily involved two teams of investigators in the Division of Genetic Medicine: Eric Gamazon, PhD, and Nancy Cox, PhD, using computational genetics and large databases, and Gokhan Unlu, PhD, and Ela Knapik, MD, studying gene function in zebrafish.”This iteration between statistical genetics analyses and biobanks and studies in animal models provides a framework that can be used to understand what a gene does within the context of the human phenome — all the diseases and traits included in electronic health records,” said Gamazon, research instructor in Medicine.The studies had their start several years ago when Gamazon and Cox, Mary Phillips Edmonds Gray Professor of Genetics and director of the Vanderbilt Genetics Institute, developed a computational method called PrediXcan that correlates genetically regulated gene expression with phenotypes. In the current work, they applied PrediXcan to BioVU, Vanderbilt’s DNA biobank and de-identified electronic health records, to generate a comprehensive catalog of associations between gene expression and clinical traits.Among the associations in this catalog, which they call PredixVU, the gene GRIK5 stood out. Reduced expression of GRIK5, which encodes a glutamate receptor subunit, was associated with 18 different eye diseases ranging from retinal detachment to cataract to glaucoma.”This was very unusual — the expectation was that a gene might be associated with four or five disease phenotypes,” said Knapik, associate professor of Medicine and Cell and Developmental Biology.The relationship of GRIK5 to eye phenotypes was also unexpected, Knapik added. GRIK5 has mostly been studied for its role in brain signaling and cognition.To explore the role of GRIK5 in zebrafish, Unlu used two approaches (CRISPR gene editing and morpholino oligonucleotides) to delete or reduce expression of GRIK5. The most striking finding in the zebrafish with reduced or no GRIK5 was bleeding.Related StoriesGenetic contribution to distractibility helps explain procrastinationAn active brain and body associated with reduced risk of dementiaNew therapy shows promise in preventing brain damage after traumatic brain injury”This was a complete surprise. There was no previous knowledge that GRIK5 had anything to do with the blood or vasculature,” Knapik said.Gamazon and Cox returned to the databases to search for evidence of patients who have both eye and vascular diseases.They analyzed electronic health records for more than 2.6 million Vanderbilt subjects and found significant comorbidity of eye and vascular diseases, and they confirmed this comorbidity using an insurance claims dataset of 150 million individuals. Unlu and Knapik continued their studies in zebrafish. They used the morpholino approach to reduce expression of GRIK5 in a zebrafish line with glowing green blood vessels and found reduced numbers of blood vessels and other vascular abnormalities in the eye, brain and trunk. They labeled the plasma with nanobeads and found leaking blood vessels in the eye, brain and ear.”Our studies show that not only the architecture of the vasculature but also the function — keeping the blood inside — is compromised in zebrafish with reduced GRIK5 expression,” said Unlu, research fellow in Genetic Medicine.In further computational studies of genotyped BioVU participants, Gamazon and Cox demonstrated an association of reduced genetically predicted GRIK5 expression with comorbid vascular and eye diseases.The researchers propose that reduced GRIK5 expression compromises vascular perfusion to the eye, leading to late-onset diseases like cataracts and glaucoma.Further studies are needed to understand the precise role of GRIK5 in the vasculature — and how defects lead to eye diseases, but the framework from these studies can be broadly applied, Knapik said.”I am a developmental geneticist. We do forward genetics in zebrafish: we make changes in the genome and study the phenotypes that result,” she said. “On the human side, Mother Nature has made changes in our genomes. And the health care system is phenotyping every day and keeping the results in electronic health records. Scientists can now use the approach we’ve demonstrated to understand the mechanisms of human disease.”
We are looking for similarities and differences between the tactical behavior of women’s and men’s national teams with the aim of drawing comparisons between different countries in Europe. In order to avoid any gender-specific bias in the evaluation we rely on position data instead of the usual video data.” Reviewed by Alina Shrourou, B.Sc. (Editor)Jun 29 2019In modern football, tactics are relevant across all age groups and performance levels. Yet for a long time they have received little attention in the training process. This is why tactical performance today offers such enormous potential. In a new project, sport scientists at the German Sport University Cologne have been comparing the soccer-specific tactical performance of male and female players in Europe with the help of position data. The study is sponsored by the Union of European Football Associations (UEFA).In the run-up to the Women’s World Cup a provocative advertising spot showed the German women’s footballers with a humorous text based on the cliché that many have probably encountered before: Women’s soccer is different from men’s.”Like amateur football, only in slow motion” says the ad.But humor apart, where objectively do the soccer-style differences lie between men and women, and how do these compare across Europe?Prof. Daniel Memmert is Head of the study: Newly developed key performance indicators and sport informatics analysis methods based on artificial neural networks have been used as objective analysis tools.The project carried out by the Institute of Exercise Training and Sports Informatics was selected by UEFA as one of only six projects (approval rate: 10%) to receive funding. The study’s findings will enable objective conclusions to be drawn about the training of men and women players in their different cultures, thus contributing to the further development and professionalisation of women’s football in the field of tactics, while supporting efforts to promote public awareness of women’s football as an attractive sport on the basis of objective evaluation criteria. Source:German Sport University
Kawhi Leonard and LeBron James https://images.performgroup.com/di/library/NBA_Global_CMS_image_storage/8f/60/kawhi-lebron-062519-ftr-gettyjpg_tlbddpwzd72b1pkafwplq6eag.jpg?t=-1875093893&w=500&quality=80Irving: I think we’re going to be able to call them the LM Clippers and LM Lakers instead of LA … it’s going to be load management city in Los Angeles next season, which makes me think that their durability may not factor into this as much as it once would have.After seeing how much that paid off for Kawhi and the Raptors this past season, I don’t see why both the Lakers and Clippers wouldn’t take a similar approach with their stars this season. I think when Kawhi, PG, AD and LeBron are all on the floor, we’re going to see the most refreshed and rested versions of themselves.Even though injuries, of course, are unpredictable.Rafferty: That’s fair.I will say this – my gut leans towards Leonard and George, but it’s more because I don’t know for certain what version of LeBron we’re going to get next season. He was still one of the best players in the league when he was healthy, but he wasn’t quite the same player as the season before.I just don’t know if we can expect him to be an MVP type player in the regular season at his age anymore.The playoffs are a different story…McGregor: Is it definitely because of age? Or do you think that insane eight-year run had a hand in it, to the point where he could bounce back this upcoming year?Rafferty: I think it’s a bit of both. It’s just tough for players to keep playing at this high of a level this late into their careers. There’s basically no precedent. LeBron is different, but I’m just not sure what quite to expect.MORE: Why Leonard and George make Clippers title favouritesIrving: I think – if he plays enough games – LeBron is going to have a statement season and win MVP. The “change” to being labeled a point guard is an intriguing storyline. After making 11 straight All-NBA First Teams, he made the All-NBA Third Team last season. He missed the playoffs for the first time since Year 2 in the league.All these things are stacking up for a ridiculous bounce-back season for The King. Maybe I’m giving him too much benefit of the doubt, but I’m also just paying the respect he’s earned over the course of his career.McGregor: I don’t think there’s such a thing as giving Bron too much benefit of the doubt – he’s definitely earned it.Rafferty: To be clear, I could totally see that happening as well. I guess I’m just lowering my expectations because of what happened last season and where he’s at in his career.Here’s another question: is LeBron still the best player out of the four of them? Or is it Kawhi?Irving: 2K tells us they’re equal at a 97 overall … but if we’re talking about paying our respects, I think it’s Kawhi after this past year.Rafferty: So if Kawhi is the best player, why aren’t the Clippers the better duo? Is Davis that much better than George?McGregor: But seriously, at his peak, yes. I think AD has a higher ceiling and floor.Honestly, I’m gonna go out on a limb here and say it: I’m not sure how sustainable what we saw from Leonard and George last year really is.Kawhi absolutely went out of his mind to have an insane run this past postseason. It’s by far one of the most impressive things I’ve ever seen. What PG did during the regular season, is pretty similar in my eyes – he put forth career-best numbers, even though he tailed off towards the end due to his injuries.I liken it to a guy getting hot in a game. You can’t expect him to do it all the time. We saw things out of the ordinary from Kawhi and PG which speaks volumes of what they’re capable of, but I’m not comfortable just saying that will be the norm.You’ve also got to take their situations into account and how that allowed them to be who they were last season.Irving: I think AD is that much better than PG just based off of what we’ve seen consistency-wise over the course of their careers so far. But I’m not counting out George putting together another season just like last year.There’s going to be less attention on him on the offensive end than there ever has been in his career. But until I definitively see him doing it again, I’m saying AD is that much better.MORE: How Lakers signings help LeBron and DavisRafferty: One thing that I don’t think we’re paying enough attention to is that Leonard and George might be the best defensive tandem we’ve seen since Michael Jordan and Scottie Pippen.That’s something else that tips the scales in their direction because LeBron certainly isn’t the defender he once was.The Lakers as a whole will be interesting defensively. Like how do they match up with the Houston Rockets, a team built around two perimeter players in Russell Westbrook and James Harden?McGregor: While they’re older, the Lakers have brought in Avery Bradley and Danny Green – two guys who have been known for their perimeter defence. Let’s not forget AD is on the backend to protect the rim.Factor in a defensive-minded coach in Frank Vogel and they could schematically cover up any deficiencies.Irving: I think it’s safe to say defensively the edge goes to the Clippers. Even though AD is a top-tier defender in the league, like Scott said, this duo of Kawhi and PG has the chance to be historic on that end of the floor.Rafferty: So now that we’ve talked this out, has your opinion changed since we started this discussion? Scott Rafferty (@crabdribbles): Both L.A. teams have made big moves this offseason. The Lakers kicked things off by trading for Anthony Davis to pair with LeBron James in the twilight of his career. The Clippers, meanwhile, won free agency by signing Kawhi Leonard and trading for Paul George in a deal nobody saw coming. It’s safe to say that the two best duos in the league are now in Los Angeles. But of the two, which one do you think is better?Gilbert McGregor (@GMcGregor21): It’s tough, but give me LeBron and AD. I think both guys are coming with something to prove this upcoming season and we’re going to see them at peak-level play … which is top-five in the league.Kyle Irving (@KyleIrv_): Deciphering which is the better of these two duos really is as tough as it gets. My heart is telling me it’s Kawhi and PG, but my gut is telling me it’s LeBron and AD, so I’m with Gil on this one.Rafferty: I feel the same way – this is about as tough as it gets – but my gut is leaning towards Leonard and George. I think their ceiling on both ends of the court is higher than LeBron and AD’s.Irving: I think the transition of Kawhi and PG playing together will be smoother from the get-go than LeBron and AD. But as Gil said, LeBron and AD both have a chip on their shoulder going into this season. LeBron still has a lot to prove to the Kobe-loving Lakers fan base and AD is trying to prove he can win.It’s scary to think about that duo playing with that type of motivation.McGregor: That’s exactly what I was thinking, too. We all know last year was FAR from what LeBron wanted in Year 16 and he definitely hears the chatter of his falling off. I think the drama surrounding Davis’ final season as a Pelican has caused some people to forget just how good he is.They probably wouldn’t admit this, either, but I think the notion that they aren’t the best duo in their own building will even be extra motivation.On the flip side, I have some concerns about the durability of the Clippers duo.MORE: How do Davis and LeBron fit together?Rafferty: Do you not have some concerns about the durability of LeBron and AD, though? LeBron has a ton of mileage – he’s going to climb into the top 10 all-time in minutes played next season – and Davis has suffered a number of injuries in his career.McGregor: On the LeBron front, I’m not too worried.The amount of time and money he invests in his health leads me to believe that last year was an anomaly and more of a product of his having essentially played 10 seasons in eight years. His body finally gave in, but he essentially rested/recovered for a third of last season and is coming off of his longest offseason since he was 20-years-old.AD is a bit more of a question mark, but I believe a change of scenery can have a number of positive effects, including for his health. He didn’t add too much mileage on his body last season, either, and that was more a product of the trade saga rather than durability. McGregor: I haven’t changed my stance at all, I’m still giving LeBron and AD a slight edge … but ask me on a different day and my answer could change. It’s that close and there are a couple of unknowns still.Irving: I’m still sticking to my gut with LeBron and AD too. I don’t know how this got more difficult to decide because it was nearly impossible not to ride the fence on this from the start, but after this chat, it’s made me realize it’s even closer than I already had thought.The views on this page do not necessarily reflect the views of the NBA or its clubs. (NBA Getty Images)
FILE PHOTO- A view of the damage caused by cyclone ‘Gaja’, after it hit Velankanni, in Nagapattinam district of Tamil Nadu, Friday, Nov. 16, 2018. – PTI relief and aid organisation SHARE SHARE EMAIL The Tamil Nadu government Thursday sought about Rs 15,000 crore as central assistance towards relief and rehabilitation activities in Cyclone Gaja-hit districts of the state. Chief Minister K Palaniswami, who met Prime Minister Narendra Modi here with a plea for central assistance for various sectors in the affected districts, said the death toll from Cyclone Gaja stood at 63. “I have submitted a memorandum to the Prime Minister detailing the extent of the damage caused by the cyclone,” he told reporters in Delhi, adding the state has sought about Rs 15,000 crore. He said he had also urged Modi to depute a central team to assess the damage, besides seeking an immediate release of nearly Rs 1500 crore towards “temporary renovation” activities. To this, the Prime Minister has given an assurance to depute a central team soon, the chief minister said. According to the abstract of the memorandum submitted to Modi by the Chief Minister, Tamil Nadu has sought a total sum of Rs 14,910 crore towards permanent renovation activities in various areas, including the power sector which has been badly hit. Over one lakh electric poles had been uprooted and a significant number of power sub-stations damaged, with reports suggesting that many parts are still without power. Cyclone Gaja had crossed the state coast early on November 16 between Nagapattinam, about 300 km from here, and nearby Vedaranyam. The Tamil Nadu government has already released a sum of Rs 1,000 crore for immediate relief and rehabilitation efforts in the affected areas. Palaniswami further said the death toll stood at 63, even as 3.41 lakh houses were damaged, while 1.04 lakh heads of cattle and birds perished following the cyclone. Noting that as many as 11.32 lakh trees had been uprooted, he said 7.27 lakh of them have been cleared. Around 3.78 lakh people were lodged in about 550 relief camps, even as relief and renovation work was on, he said. Over 1.03 lakh electric poles were either uprooted or mangled and 40 percent of them have been repaired. Supply of electricity and drinking water was also being gradually restored, he added. Recalling the compensation provided to families of deceased (Rs 10 lakh), he said it was more than what the earlier DMK government had given during cyclones in 2008 and 2010. The DMK had given Rs two lakh, he claimed. He had taken a helicopter from Tiruchirappalli to Pudukottai and Thanjavur districts on Tuesday to visit the affected parts but could not land at Nagapattinam and Thiruvarur due to inclement weather following which he had to cut short his tour. Published on COMMENTS COMMENT Tamil Nadu November 22, 2018 SHARE cyclones